Cincinnati +8.5 (at New England)
The Bengals have been diabolical this season and play without Ja’Marr Chase this week but teams on a winning streak of eight-plus games cover at just 39% and teams off playing the Jets are 19-38 against the spread.
Detroit -10.5 (v NY Giants)
Jared Goff and Dan Campbell have covered 13 straight off a loss while Goff is 24-7 against the number when playing indoors.
Dallas +3.5 (v Philadelphia)
Dak Prescott has a great 17-6 cover record at home against division rivals while Jalen Hurts is 4-8-1 against the spread on the road against NFC East opposition.
LA Rams -6.5 (v Tampa Bay)
The NFC West is an incredible 18-7-1 against the spread this year while Baker Mayfield is 4-9 against the spread in primetime.
Carolina @ $3.60 (at San Francisco)
The 49ers have failed to cover their last 12 at home off a win and their last nine on extended rest so this is a big spot to take the Niners on.
Under 43.5 Buffalo-Houston
The under is 17-5 when Texans QB CJ Stroud plays at home with the under hitting at 58% in primetime games.
Under 50.5 Indianapolis-Kansas City
The under is 14-4 in Patrick Mahomes games when the total is above 50 while it hits at 69% when a road team is out of a bye.
Over 50.5 New England-Cincinnati
The over is 11-2 in Bengals home games across the last two seasons with the Bengals conceding a whopping 33.4 points per game, 4.1 more than the second worst team.
Under 43.5 Buffalo-Houston
The under is 17-5 when Texans QB CJ Stroud plays at home with the under hitting at 58% in primetime games.
LA Rams -6.5 (v Tampa Bay)
The NFC West is an incredible 18-7-1 against the spread this year while Baker Mayfield is 4-9 against the spread in primetime.
Carolina @ $3.60 (at San Francisco)
The 49ers have failed to cover their last 12 at home off a win and their last nine on extended rest so this is a big spot to take the Niners on.
Cincinnati +8.5/Detroit -10.5/Baltimore -13.5/Seattle -13.5 ($12.82)
The Bengals and Lions are both listed among the best bets for the week. The Ravens have covered 10 of the last 12 against the Jets. Seattle have covered 10 of 13 on the road under Mike MacDonald.
Arizona +2.5/New Orleans/Dallas +3.5 ($6.52)
The NFC West is 18-7 against the spread outside their division so the Cards are an excellent bet getting points at home against the Jags. Kirk Cousins is 0-4 against the spread all-time against the Saints so betting the tough New Orleans outfit. Dallas are listed among the best bets.
Jameson Williams ($9 First, $2.20 Anytime)
The Lions have worked hard to get Jameson Williams more ball after the bye and it has resulted in him scoring each of the last three weeks with 14 catches for 273 yards.
Mark Andrews TD/Jaxon Smith-Njigba TD/Jahmyr Gibbs ($7.75)
Betting players on three double digit favourites this week. Mark Andrews has three touchdowns the last three weeks. Jaxon Smith-Njigba has four touchdowns in his last six games. Jahmyr Gibbs has 10 touchdowns this season.
Shedeur Sanders Under 162.5 Pass Yards/Brock Bowers Over 65.5 Receiving Yards/Tre Tucker Under 36.5 Receiving Yards ($6.11)
Sanders looked completely out of his depth when coming on for his first NFL action against the Ravens. Brock Bowers has topped 70 yards in two of his last three with Chip Kelly intent on getting his tight end the ball. Tucker has topped 40 yards in just one of his last four and wideouts will get very little love with Myles Garrett having another incredible season.